What’s the difference between chemo and radiation? These two forms of cancer treatment are often mentioned in the same breath, but they are quite different in their mechanisms, applications, and side effects. Understanding these differences can help patients and their families make informed decisions about their treatment options.
Chemotherapy, also known as chemo, is a systemic treatment that uses drugs to kill cancer cells. These drugs are typically administered intravenously or orally and can affect cells throughout the body. The goal of chemotherapy is to destroy cancer cells and prevent them from dividing and growing. It is commonly used to treat various types of cancer, including breast, lung, and colorectal cancer.
On the other hand, radiation therapy is a localized treatment that uses high-energy beams, such as X-rays, to kill cancer cells or prevent them from multiplying. The radiation can be delivered externally, known as external beam radiation therapy (EBRT), or internally, known as brachytherapy. Radiation therapy is often used to treat cancer in specific areas of the body, such as the brain, lung, or breast.
One of the main differences between chemo and radiation is their mode of action. Chemo works by targeting rapidly dividing cells, which is why it can affect both cancer cells and healthy cells that divide quickly, such as hair follicles and the lining of the mouth and intestines. This is why chemotherapy can cause side effects like hair loss, nausea, and fatigue. In contrast, radiation therapy targets specific areas of the body, minimizing damage to healthy cells and reducing the risk of side effects.
Another difference is the duration and frequency of treatment. Chemo is usually given in cycles, with a period of treatment followed by a rest period. The number of cycles and the length of each cycle depend on the type of cancer and the individual’s response to treatment. Radiation therapy, on the other hand, is typically given in daily sessions over a few weeks, depending on the size and location of the tumor.
Side effects also vary between chemo and radiation. Chemo can cause a wide range of side effects, including fatigue, nausea, vomiting, hair loss, and an increased risk of infection. Radiation therapy can cause side effects such as fatigue, skin irritation, and in some cases, long-term damage to organs near the treatment area.
In conclusion, while both chemo and radiation are effective cancer treatments, they differ in their mechanisms, applications, and side effects. Chemo is a systemic treatment that can affect cells throughout the body, while radiation therapy is a localized treatment that targets specific areas. Understanding these differences can help patients and their healthcare providers choose the most appropriate treatment plan for their individual needs.